The Myers and Hendon Labs congratulate Frank Yao and Yu Gan on their well-deserved doctoral degrees from Columbia University. Yu and Frank pioneered imaging and analysis techniques to quantify collagen fiber architecture in the human cervix. Their work defines cervical anisotropic material properties, helping us understand the mechanical integrity of the cervix during pregnancy. Pictured here: Yu Gan, Christine Hendon, Kristin Myers, and Frank Yao
Andrea’s first paper on calculating the effects of cervical geometry and cervical material properties on the mechanical loading of the cervical os has been published by the ASME Journal of Biomechanical Engineering. The paper is entitled, A Parameterized Ultrasound-Based Finite Element Analysis of the Mechanical Environment of Pregnancy, and the methodology takes advantage of ultrasound data of the maternal anatomy to build parametric models of the pregnant abdomen.
The Myers lab is honored to announce Prof. Myers will receive the 2017 ASME Y.C. Fung Young Investigator award. The award will be given at this year’s Summer Biomechanics, Bioengineering, and Biotransport Conference in Tucson, AZ. The full announcement can be read here.
With our collaborator Christine Hendon in Electrical Engineering here at Columbia, we have characterized the collagen fiber directionality of the human cervix using optical coherence tomography (OCT). Our results are now published in a study entitled, Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Women on the PLOS ONE website. The study is co-authored by Wang (Frank) Yao from the Myers lab and Yu Gan from the Hendon lab.
All raw data are available on the Columbia University Academic Commons website (http://dx.doi.org/10.7916/D8BG2PCX).
Read a recent article about our pregnancy biomechanics work featured in ASME online.
Our paper titled, “Material properties of mouse cervical tissue in normal gestation” has been published in Acta Biomaterialia. This paper outlines our experimental and inverse finite element methods to calculate the material property changes of the mouse cervix in a normal pregnancy. Here, we found that cervical stiffness in a mouse decreases by 4 orders of magnitude within a 19-day mouse pregnancy. Our raw data from this study is also available at the Columbia University Library’s Academic Commons (http://dx.doi.org/10.7916/D8DN44QW)
Our preterm birth research is featured in the Fall/Winter 2015 Columbia Medicine Alumni Magazine along with all of our Columbia colleagues working towards understanding and reducing the burden of preterm birth.