What is the role of small leucine-rich proteoglycans (SLRPs) in cervical remodeling during pregnancy? In collaboration with the Mahendroo lab at the University of Texas Southwestern Medical Center, the combination of imaging, immunohistochemistry, collagen crosslink analysis, and mechanical testing reveals an important regulatory role of SLRPs in the uterine cervix.
This article is written by Mariano Colon-Caraballo (from collaborator Mala Mahendroo’s lab), co-authored by Nicole Lee.
Article – Matrix Biology
Novel regulatory roles of small leucine-rich proteoglycans in remodeling of the uterine cervix in pregnancy