With our collaborator Christine Hendon in Electrical Engineering here at Columbia, we have characterized the collagen fiber directionality of the human cervix using optical coherence tomography (OCT). Our results are now published in a study entitled, Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Women on the PLOS ONE website. The study is co-authored by Wang (Frank) Yao from the Myers lab and Yu Gan from the Hendon lab.
All raw data are available on the Columbia University Academic Commons website (http://dx.doi.org/10.7916/D8BG2PCX).
Read a recent article about our pregnancy biomechanics work featured in ASME online.
Kyoko and Michael have successfully defended their doctoral thesis – congratulations!
Our preterm birth research is featured in the Fall/Winter 2015 Columbia Medicine Alumni Magazine along with all of our Columbia colleagues working towards understanding and reducing the burden of preterm birth.
The Myers lab has open graduate research positions in reproductive biomechanics. The job tasks include: the mechanical testing of collagenous tissues, investigating steroid hormone and extracellular matrix biochemistry, hyperelastic material constitutive modeling, analysis of the growth and remodeling of biologic tissues, and finite element modeling. Please contact firstname.lastname@example.org with your CV if interested.
Google Scholar Profile [link]
PubMed NCBI [link]
Scopus Author Page [link]
Find our new finite element study of pregnancy on-line in Computer Methods in Biomechanics and Biomedical Engineering. This study calculates the mechanical loading on the cervix for two pregnant patients, using geometry derived from MRI scans and material parameters from our previous experiments.
The World Health Organization released new statistics on the rate of preterm birth around the world. The bottom line is preterm birth rates are still high. About 15 million babies are born preterm every year. In 2013 almost 1 million babies died from complications related to preterm birth. Increased knowledge on the cause of preterm and better solutions to prevent it from happening are much needed.
The Myers lab is featured in this Summer’s edition of Connections (pages 7-8) – a Newsletter from the Columbia University Medical Center Department of Obstetrics and Gynecology. The article details our collaborative relationship with clinicians and scientists to unravel the causes of preterm birth. Here, we discuss how we use our finite elements models of pregnancy to understand how the cervix acts as a mechanical barrier to protect the fetus.