The Myers lab had the pleasure to join fellow mechanics colleagues and other former students to honor Alan Wineman in his 50th year of teaching at the University of Michigan at this year’s USNCTAM meeting at MSU. Our work in trying to understand and model the complex collagen remodeling behavior of cervical tissue during pregnancy is directly inspired by Prof. Wineman’s work in scission and crossliking of rubbers. Kudos, Alan, to an amazing career and inspiring so many students!
Author Archives: kristinmyerscolumbia
A recent Wall Street Journal Article (published: Tuesday, July 16th, 2013) discusses the possible detrimental effects of long-term bed rest during pregnancy. Often bed rest is prescribed to prevent preterm birth due to premature cervical dilation (aka cervical insufficiency). However, since not much is known about the mechanics of cervical remodeling and dilation, the efficacy of bed rest to prevent preterm birth is unknown.
Our paper entitled “Interstitial growth and remodeling of biological tissues: Tissue composition as state variables” reviews the latest literature of cervical tissue remodeling during pregnancy and details a constitutive remodeling framework for evoling tissue properties based on the evolution of the tissue’s microstructure. This paper was co-authored by Gerard Ateshian and is available online.
The Myers lab presented two posters at this years SGI meeting in Orlando Florida. Both posters presented our investigation into the correlation between cervical mechanical strength and collagen crosslink density during cervical remodeling. Here, Kyoko explains her methodology to determine the swelling characteristics of the cervix during pregnancy.
Our manuscript detailing the direct measurment of hydraulic permeaility of human cervix tissue is now online at the ASME Journal of Biomechanical Engineering website. See details below:
Eli and Kyoko developed new methods to mechanically test uterine tissue to understand its function during pregnancy. Congratulations to Eli for an excellent research poster at this year’s Columbia University Summer Undergraduate Research Fellowship (SURF) poster session at the Low Library.