Our new manuscript detailing the mechanical properties of the cervix subjected to infection- and hormone-mediated premature cervical remodeling is now online in Acta Biomaterialia.
The article is authored by Charles Jayyosi in collaboration with Mala Mahendroo’s lab at UTSWMC.
Article – Acta Biomaterialia:
The mechanical response of the mouse cervix to tensile cyclic loading in term and preterm pregnancy
Raw Data – Columbia Academic Commons:
The Myers Lab joined Columbia Doctors and the team from the CUMC Preterm Birth Prevention Center at this year’s March of Dimes Walk for Babies. Thank you to all that walked and to the March of Dimes for contributing funds to our research. Pictured here from the Myers Lab: Charles Jayyosi, Shuyang Fang, Lei Shi, and Nicole Lee. Photo credit: Joy Vink.
Please check out the Columbia News article on our research.
The Myers Lab celebrated our Spring 2017 academic semester – congrats to Shu, Lei, and Nicole for passing their doctoral qualifying exams, Andrea for publishing her first paper, Frank for defending his doctoral thesis, and Charles for winning the Burroughs Wellcome Fund Collaborative Research Travel Grant. Pictured here (L-R): Andrea Westervelt, Michael Fernandez, Kristin Myers, Shuyang Fang, Lei Shi, Nicole Lee, Frank Yao, and Charles Jayyosi.
Along with our long-time colleague David Elad from Tel Aviv University and the Department of Biomedical Engineering at Columbia University, we are happy to announce the online release of our Biomechanics of the Human Uterus review article. The article is published in WIRES Systems Biology and Medicine.
The Myers and Hendon Labs congratulate Frank Yao and Yu Gan on their well-deserved doctoral degrees from Columbia University. Yu and Frank pioneered imaging and analysis techniques to quantify collagen fiber architecture in the human cervix. Their work defines cervical anisotropic material properties, helping us understand the mechanical integrity of the cervix during pregnancy. Pictured here: Yu Gan, Christine Hendon, Kristin Myers, and Frank Yao
Andrea’s first paper on calculating the effects of cervical geometry and cervical material properties on the mechanical loading of the cervical os has been published by the ASME Journal of Biomechanical Engineering. The paper is entitled, A Parameterized Ultrasound-Based Finite Element Analysis of the Mechanical Environment of Pregnancy, and the methodology takes advantage of ultrasound data of the maternal anatomy to build parametric models of the pregnant abdomen.
The Myers lab is honored to announce Prof. Myers will receive the 2017 ASME Y.C. Fung Young Investigator award. The award will be given at this year’s Summer Biomechanics, Bioengineering, and Biotransport Conference in Tucson, AZ. The full announcement can be read here.
With our collaborator Christine Hendon in Electrical Engineering here at Columbia, we have characterized the collagen fiber directionality of the human cervix using optical coherence tomography (OCT). Our results are now published in a study entitled, Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Women on the PLOS ONE website. The study is co-authored by Wang (Frank) Yao from the Myers lab and Yu Gan from the Hendon lab.
All raw data are available on the Columbia University Academic Commons website (http://dx.doi.org/10.7916/D8BG2PCX).
Read a recent article about our pregnancy biomechanics work featured in ASME online.