Our paper titled, “Material properties of mouse cervical tissue in normal gestation” has been published in Acta Biomaterialia. This paper outlines our experimental and inverse finite element methods to calculate the material property changes of the mouse cervix in a normal pregnancy. Here, we found that cervical stiffness in a mouse decreases by 4 orders of magnitude within a 19-day mouse pregnancy. Our raw data from this study is also available at the Columbia University Library’s Academic Commons (http://dx.doi.org/10.7916/D8DN44QW)
Author Archives: ky2218
Our clinical collaborator, Dr. Joy Vink has been selected as a 2015 Louis V. Gerstner Jr. Scholar. This program supports physician-scientists at the Columbia University Medical Center to conduct translational research designed to bring new treatments for patients.
Congratulations Dr. Vink!
Great news! Dr. Myers recently won the NSF CAREER award for her project, “Growth and Remodeling of the Uterine Cervix during Pregnancy”.
This award will help support our ongoing investigation of the underlying causes of preterm cervical remodeling. Specifically, this work will focus on determining the biochemical and mechanical property changes that occur under various hormonal cues during pregnancy.
Congratulations Dr. Myers!
Publication Alert: Collagen Crosslinks and Tensile Structural Properties in Mouse Cervix Throughout Gestation
Our paper titled, “Quantitative Evaluation of Collagen Crosslinks and Corresponding Tensile Mechanical Properties in Mouse Cervical Tissue during Normal Pregnancy” has been published in the open source journal, PLOS ONE. Here, we report our findings on both mature and immature collagen crosslink density throughout mouse gestation and how it correlates to tensile structural properties.
Thank you to our collaborators and co-authors for your contributions!
A couple weeks ago, Kyoko went to Poly Prep to participate in Women’s Innovation Symposium in Engineering (WISE) . The symposium was a great opportunity for girls in middle to high school interested in becoming engineers. The day included a keynote speaker, who talked about what engineers do, a breakout workshop session, and concluded with a presentation from the girls about what they learned. Kristin and Kyoko designed a workshop to teach girls about the strength of materials by running some experiments to measure the mechanical properties of different rubber specimens . The girls had a great time playing with spring gauges and calipers, and got first hand experience on how important it is to run careful experiments! Check out some pictures here.
It was a fun event and a great opportunity to not only to reach out to young aspiring lady engineers, but also to network with other ladies in engineering. We hope to be participating again next year!
A mother in Berlin is the first woman ever to give birth inside a MRI scanner!
Doctors in Berlin designed an open MRI scanner to capture some amazing images before, during, and after childbirth. Just another example of how medical imaging is really progressing right now. The associated paper also mentions the “mechanical factors” of birth. Maybe this will inspire more engineers to study reproductive biomechanics…
Human Birth Observed in Real-time Open Magnetic Resonance Imaging [Science Direct]