Find our new finite element study of pregnancy on-line in Computer Methods in Biomechanics and Biomedical Engineering. This study calculates the mechanical loading on the cervix for two pregnant patients, using geometry derived from MRI scans and material parameters from our previous experiments.
Our clinical collaborator, Dr. Joy Vink has been selected as a 2015 Louis V. Gerstner Jr. Scholar. This program supports physician-scientists at the Columbia University Medical Center to conduct translational research designed to bring new treatments for patients.
Congratulations Dr. Vink!
Great news! Dr. Myers recently won the NSF CAREER award for her project, “Growth and Remodeling of the Uterine Cervix during Pregnancy”.
This award will help support our ongoing investigation of the underlying causes of preterm cervical remodeling. Specifically, this work will focus on determining the biochemical and mechanical property changes that occur under various hormonal cues during pregnancy.
Congratulations Dr. Myers!
The World Health Organization released new statistics on the rate of preterm birth around the world. The bottom line is preterm birth rates are still high. About 15 million babies are born preterm every year. In 2013 almost 1 million babies died from complications related to preterm birth. Increased knowledge on the cause of preterm and better solutions to prevent it from happening are much needed.
Publication Alert: Collagen Crosslinks and Tensile Structural Properties in Mouse Cervix Throughout Gestation
Our paper titled, “Quantitative Evaluation of Collagen Crosslinks and Corresponding Tensile Mechanical Properties in Mouse Cervical Tissue during Normal Pregnancy” has been published in the open source journal, PLOS ONE. Here, we report our findings on both mature and immature collagen crosslink density throughout mouse gestation and how it correlates to tensile structural properties.
Thank you to our collaborators and co-authors for your contributions!
The Myers lab is featured in this Summer’s edition of Connections (pages 7-8) – a Newsletter from the Columbia University Medical Center Department of Obstetrics and Gynecology. The article details our collaborative relationship with clinicians and scientists to unravel the causes of preterm birth. Here, we discuss how we use our finite elements models of pregnancy to understand how the cervix acts as a mechanical barrier to protect the fetus.